生物接合化學(xué)提供了對接合化學(xué)多學(xué)科、突破性研究的集中訪問。報告了活性分子與生物聚合物、表面和其他材料共價結(jié)合的關(guān)鍵進(jìn)展。覆蓋范圍包括抗體及其片段、核酸及其類似物、脂質(zhì)體成分和其他生物活性分子相互結(jié)合或與任何增加有用性質(zhì)的分子群結(jié)合。主題包括共軛制備和表征的研究;共軛方法的體內(nèi)應(yīng)用;抗體、基因工程片段和其他免疫化學(xué)物質(zhì)的分子生物學(xué)方面;共軛化學(xué)與共軛物生物學(xué)性質(zhì)之間的關(guān)系。
Bioconjugate Chemistry provides centralized access to multidisciplinary, groundbreaking research in conjugation chemistry. It reports on key advances concerning the covalent attachment of active molecules to biopolymers, surfaces, and other materials. Coverage spans conjugation of antibodies and their fragments, nucleic acids and their analogs, liposomal components, and other biologically active molecules with each other or with any molecular groups that add useful properties. Topics include studies of conjugate preparation and characterization; in vivo applications of conjugate methodology; molecular biological aspects of antibodies, genetically engineered fragments, and other immunochemicals; and the relationships between conjugation chemistry and the biological properties of conjugates.
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