《大腦皮層》發表關于大腦皮層包括海馬的發育、組織、可塑性和功能的論文。與大腦皮層有明顯相關性的研究，如丘腦皮質關系或皮質-皮質下相互作用也包括在內。該雜志是多學科的，涵蓋了多種現代神經生物學和神經心理學技術，包括解剖學、生物化學、分子神經生物學、電生理學、行為、人工智能和理論建模。除了研究文章，特別功能，如簡要評論，書評和評論包括。《大腦皮層》每年出版8期。

Cerebral Cortex publishes papers on the development organization plasticity and function of the cerebral cortex including the hippocampus. Studies with clear relevance to the cerebral cortex such as the thalamocortical relationship or cortico-subcortical interactions are also included. The journal is multidisciplinary and covers the large variety of modern neurobiological and neuropsychological techniques including anatomy biochemistry molecular neurobiology electrophysiology behavior artificial intelligence and theoretical modeling. In addition to research articles special features such as brief reviews book reviews and commentaries are included. Cerebral Cortex is published 8 times yearly.