該雜志發表了關于計算力學、計算物理、計算化學和計算生物學等與固體、流體、氣體、生物材料和其他連續性有關的原始合理的永久價值的研究論文。不同的長度尺度（量子尺度、納米尺度、微觀尺度、介子尺度和宏觀尺度）和不同的時間尺度（皮秒到小時尺度）都很有趣。特別鼓勵處理多物理問題的論文，以及處理力學、化學和生物學接口的論文。新的計算方法和更有效的算法，最終使近實時計算成為可能，是受歡迎的。本文對無網格法、網格約簡法等新方法進行了研究。

This journal publishes original research papers of reasonable permanent value, in the areas of computational mechanics, computational physics, computational chemistry, and computational biology, pertinent to solids, fluids, gases, biomaterials, and other continua. Various length scales (quantum, nano, micro, meso, and macro), and various time scales( picoseconds to hours) are of interest. Papers which deal with multi-physics problems, as well as those which deal with the interfaces of mechanics, chemistry, and biology, are particularly encouraged. New computational approaches, and more efficient algorithms, which eventually make near-real-time computations possible, are welcome. Original papers dealing with new methods such as meshless methods, and mesh-reduction methods are sought.