近四分之一世紀(jì)，隨著生物化學(xué)和分子生物學(xué)學(xué)科的飛速發(fā)展，對(duì)普通醫(yī)學(xué)、遺傳學(xué)、免疫學(xué)、發(fā)育生物學(xué)和生物物理學(xué)的發(fā)展作出了重大貢獻(xiàn)。廣泛學(xué)科的研究人員越來越需要了解當(dāng)前生物化學(xué)和分子生物學(xué)進(jìn)展的重要性，而生物化學(xué)和分子生物學(xué)界的成員本身則尋求與各自專業(yè)無關(guān)的領(lǐng)域進(jìn)展的簡明信息。生物化學(xué)和分子生物學(xué)的評(píng)論認(rèn)為，寫得好的評(píng)論文章是整合和有意義地理解大量的，經(jīng)常是矛盾的文獻(xiàn)的有效手段。綜述文章還通過綜合已知事實(shí)、富有成果的假設(shè)和新概念，為創(chuàng)造性的學(xué)術(shù)提供了機(jī)會(huì)。因此，生物化學(xué)和分子生物學(xué)的評(píng)論發(fā)表了高質(zhì)量的評(píng)論，這些評(píng)論組織、評(píng)估和介紹了生物化學(xué)和分子生物學(xué)領(lǐng)域的高影響、當(dāng)前問題的現(xiàn)狀。選題是根據(jù)杰出科學(xué)家咨詢委員會(huì)的建議進(jìn)行的，該委員會(huì)還建議具有特殊能力的作者。所選主題足夠?qū)挿海軌蛭龔V大讀者，但重點(diǎn)足夠集中，能夠在單個(gè)作者的能力范圍內(nèi)。作者的選擇是基于他們?cè)谠擃I(lǐng)域的活動(dòng)和他們證明的能力，以產(chǎn)生一個(gè)良好的書面出版物。

As the discipline of biochemistry and molecular biology have greatly advanced in the last quarter century, significant contributions have been made towards the advancement of general medicine, genetics, immunology, developmental biology, and biophysics. Investigators in a wide range of disciplines increasingly require an appreciation of the significance of current biochemical and molecular biology advances while, members of the biochemical and molecular biology community itself seek concise information on advances in areas remote from their own specialties.Critical Reviews in Biochemistry and Molecular Biology believes that well-written review articles prove an effective device for the integration and meaningful comprehension of vast, often contradictory, literature. Review articles also provide an opportunity for creative scholarship by synthesizing known facts, fruitful hypotheses, and new concepts. Accordingly, Critical Reviews in Biochemistry and Molecular Biology publishes high-quality reviews that organize, evaluate, and present the current status of high-impact, current issues in the area of biochemistry and molecular biology.Topics are selected on the advice of an advisory board of outstanding scientists, who also suggest authors of special competence. The topics chosen are sufficiently broad to interest a wide audience of readers, yet focused enough to be within the competence of a single author. Authors are chosen based on their activity in the field and their proven ability to produce a well-written publication.