《抑郁和焦慮》歡迎原創的研究和綜合評論文章，涵蓋分子遺傳、生物、心理、社會、神經化學、神經心理、生理行為、社會學、心理動力學、心理治療、認知和藥物治療方面的情緒和焦慮障礙以及人類和動物的相關現象。該雜志出版了完整的研究論文，專題評論，簡要報告，書籍報告，臨床案例研究和信件。貢獻按主題分組和發布。

Depression and Anxiety welcomes original research and synthetic review articles covering molecular genetic biopsychosocial neurochemical neuropsychological physiological behavioral sociological psychodynamic psychotherapeutic cognitive and pharmacotherapeutic aspects of mood and anxiety disorders and related phenomena in humans and animals. The journal publishes full-length Research Papers Topical Reviews Brief Reports Book Reports Clinical Case Studies and Letters. Contributions are grouped and published by topic.