《分化》是一本多學(xué)科期刊，涉及細(xì)胞分化、發(fā)育、細(xì)胞結(jié)構(gòu)和功能以及癌癥等主題。在分子水平上的真核生物分化，以及利用轉(zhuǎn)基因和定向誘變方法來解決分化問題是該雜志特別感興趣的。該雜志將發(fā)表包含上述任何領(lǐng)域原創(chuàng)作品的全文文章。我們亦會(huì)就當(dāng)前感興趣的課題發(fā)表評(píng)論。該雜志涵蓋的主要主題領(lǐng)域是:?胚胎模式和器官形成?人類發(fā)展和先天畸形?細(xì)胞譜系承諾機(jī)制?組織穩(wěn)態(tài)和致癌轉(zhuǎn)化?細(xì)胞極性的建立?干細(xì)胞分化?細(xì)胞重編程機(jī)制?差異化狀態(tài)的穩(wěn)定性?細(xì)胞和組織在體內(nèi)和體外的相互作用?發(fā)育和分化中的信號(hào)轉(zhuǎn)導(dǎo)通路?致癌和癌癥?參與細(xì)胞生長(zhǎng)和分裂的機(jī)制，特別是與癌癥有關(guān)的?再生和衰老的分化?分化過程的治療應(yīng)用

Differentiation is a multidisciplinary journal dealing with topics relating to cell differentiation, development, cellular structure and function, and cancer. Differentiation of eukaryotes at the molecular level and the use of transgenic and targeted mutagenesis approaches to problems of differentiation are of particular interest to the journal.The journal will publish full-length articles containing original work in any of these areas. We will also publish reviews and commentaries on topics of current interest.The principal subject areas the journal covers are: ? embryonic patterning and organogenesis? human development and congenital malformation? mechanisms of cell lineage commitment? tissue homeostasis and oncogenic transformation? establishment of cellular polarity? stem cell differentiation? cell reprogramming mechanisms? stability of the differentiated state? cell and tissue interactions in vivo and in vitro? signal transduction pathways in development and differentiation? carcinogenesis and cancer? mechanisms involved in cell growth and division especially relating to cancer? differentiation in regeneration and ageing? therapeutic applications of differentiation processes