《免疫學方法雜志》致力于涵蓋以下技術(shù):(1)基于抗原-抗體相互作用定量和檢測抗體和/或抗原和半抗原。(2)分離純化免疫球蛋白、淋巴因子等免疫系統(tǒng)分子。(3)分離免疫過程中重要的抗原等物質(zhì)。(四)用放射性等標記物標記抗原、抗體。(5)在體內(nèi)或體外的組織和細胞中定位抗原和/或抗體。(6)免疫感受性細胞的檢測、計數(shù)和分離。(7)細胞免疫測定。(8)細胞-細胞相互作用檢測細胞表面抗原。(9)啟動免疫和無反應。(10)移植組織。(11)研究與免疫密切相關(guān)的補體、網(wǎng)狀內(nèi)皮系統(tǒng)等。此外,該雜志還將發(fā)表關(guān)于分析免疫重要分子(如免疫球蛋白、T細胞受體和參與抗原識別、處理和表達的輔助分子)基因的組織、結(jié)構(gòu)和表達的新方法的文章。提交完整的手稿應該描述的新方法的廣泛適用性免疫學并不是簡單的應用程序的方法建立一個特定的物質(zhì)——盡管論文描述這樣的應用程序可以考慮發(fā)表一個簡短的技術(shù)注意重組技術(shù)部分將包含有關(guān)修改文章通過重組技術(shù)的分子免疫學的興趣;噬菌體顯示技術(shù)分離新型結(jié)合蛋白基因治療;轉(zhuǎn)染;和表達。免疫學協(xié)議是一節(jié)提供詳細的,一步一步的描述新的和建立的免疫學技術(shù)。也歡迎有關(guān)免疫相關(guān)受體結(jié)合位點的分子生物學分析的文章。
The Journal of Immunological Methods is devoted to covering techniques for: (1) Quantitating and detecting antibodies and/or antigens and haptens based on antigen-antibody interactions. (2) Fractionating and purifying immunoglobulins, lymphokines and other molecules of the immune system. (3) Isolating antigens and other substances important in immunological processes. (4) Labelling antigens and antibodies with radioactive and other markers. (5) Localizing antigens and/or antibodies in tissues and cells, in vivo or in vitro. (6) Detecting, enumerating and fractionating immunocompetent cells. (7) Assaying for cellular immunity. (8) Detecting cell-surface antigens by cell-cell interactions. (9) Initiating immunity and unresponsiveness. (10) Transplanting tissues. (11) Studying items closely related to immunity such as complement, reticuloendothelial system and others. In addition the journal will publish articles on novel methods for analysing the organization, structure and expression of genes for immunologically important molecules such as immunoglobulins, T cell receptors and accessory molecules involved in antigen recognition, processing and presentation. Submitted full length manuscripts should describe new methods of broad applicability to immunology and not simply the application of an established method to a particular substance - although papers describing such applications may be considered for publication as a short Technical Note The Recombinant Technology section will contain articles relating to modification by recombinant techniques of molecules of immunological interest; isolation of novel binding proteins by phage display; gene therapy; transfection; and expression. Immunology Protocols is a section providing detailed, step-by-step descriptions of new and established techniques in immunology. Articles on the molecular biological analysis of immunologically relevant receptor binding sites are also invited.
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