《病理學雜志》的主要興趣在于人類疾病的病理生理和發病機制，以及這些知識在診斷和預后中的應用。在確定內容時，主要考慮的是卓越的相關性和新穎性。該雜志歡迎對人體組織的研究，體外和體內的實驗研究，以及基于與人類疾病（包括轉基因系統）有明確關聯的動物模型的研究。研究性和診斷性病理學的方法改進也很有趣。鼓勵對病理學數據和臨床結果進行相關研究，但關于診斷病理學的純描述性論文并不被認為是該雜志的核心目的。一般來說，適當采用多種調查方法的研究比依賴單一方法的研究更為可取。插圖必須具有最高質量，才能出版。除了最初的研究論文，該雜志還尋求以各種其他形式提供快速出版，包括社論評論文章和其他既有貢獻又有索取的特色。如果論文涉及到教學方法和病理學實踐的重大發展，并且具有國際范圍和相關性，則可以接受。如果讀者的信件符合一般利益，將予以公布。總之，該雜志的目標是成為基礎生物醫學科學和臨床醫學之間的橋梁。作為大不列顛和愛爾蘭病理學會的一本雜志，它試圖反映該學會成員的廣泛科學利益，但它的精神、作者內容和目的是國際科學文獻的主要出版物。

The main interests of the Journal of Pathology lie in the pathophysiological and pathogenetic mechanisms of human disease and in the application of such knowledge to diagnosis and prognosis. In determining content the primary considerations are excellence relevance and novelty. The Journal welcomes investigative studies on human tissues experimental studies in vitro and in vivo and investigations based on animal models with a clear relevance to human disease including transgenic systems. Methodological improvements in investigative and diagnostic pathology are also of interest. Correlative studies of pathological data and clinical outcomes are encouraged but purely descriptive papers on diagnostic pathology are not considered central to the Journal's purpose. In general studies which appropriately employ multiple investigative techniques are preferred over those which rely on a single methodology. Illustrations must be of the highest quality to be acceptable for publication. As well as original research papers the Journal seeks to provide rapid publication in a variety of other formats including editorials review articles and other features both contributed and solicited. Papers covering significant developments in teaching methods and in the practice of pathology may be acceptable if they are of international scope and relevance. Correspondence from readers will be published if it is of general interest. In summary the Journal aims to serve as a bridge between basic biomedical science and clinical medicine. As a Journal of the Pathological Society of Great Britain and Ireland it seeks to reflect the broad scientific interests of the Society's membership but its ethos authorship content and purpose are those expected of a leading publication in the international scientific literature.