該雜志是跨學科的。有關神經系統對實驗損傷或意外事故的可塑性和反應、移植、神經退行性疾病以及改善再生或功能恢復的實驗策略的論文將被考慮發表。鼓勵采用新概念方法的實驗和臨床研究論文。出版的首要標準是新穎，重要的實驗或臨床相關性，以及對多學科觀眾的興趣。未麻醉動物實驗應符合美國國家科學院實驗動物資源研究所制定的實驗動物使用標準。必須證明使用麻痹劑的實驗是正確的。應隱瞞病人的身份。所有的稿件都被發送給編輯委員會成員或外部審稿人進行盲審。

The journal is interdisciplinary. Papers relating the plasticity and response of the nervous system to accidental of experimental injuries or in-terventions, transplantation, neurodegenerative disorders, and experimental strategies to improve regeneration or functional recovery will be considered for publication. Experimental and clinical research papers adopting fresh conceptual approaches are encouraged. The overriding criteria for publication are novelty, significant experimental or clinical relevance, and interest to a multidisciplinary audience. Experiments on unanesthetized animals should conform with the standards for the use of laboratory animals as established by the Institute of Laboratory Animal Resources, US National Academy of Sciences. Experiments in which paralytic agents are used must be justified. Patient identity should be concealed. All manuscripts are sent out for blind "peer review" to editorial board members or outside reviewers.