《毒理學研究》旨在發(fā)布卓越和創(chuàng)新的前沿研究,推動毒理學并具有國際影響力。文章應涵蓋毒性反應的化學或生物方面以及所涉及的機制。該期刊的范圍包括以下內容:納米毒理學,強烈鼓勵研究納米材料和與人類健康直接相關的常見納米材料的毒性反應的生化或分子機制。致癌性,包括致癌物的作用方式,遺傳毒性和突變的研究毒性的生物標志物,包括對其鑒定,驗證和利用的研究計算和預測毒理學,包括體外,體內和計算機毒性研究以及預測工具和模型的開發(fā)。鼓勵考慮采用替代方法進行體內研究。系統(tǒng)毒理學,描述化學物質對特定器官或系統(tǒng)(例如,免疫,神經,生殖,呼吸)的毒理學影響的研究,包括納入基因組學,代謝組學和蛋白質組學數(shù)據(jù)的研究風險評估,提供毒理學數(shù)據(jù)或信息的研究 - 例如危害識別,劑量反應評估風險評估或監(jiān)管制定的風險暴露評估環(huán)境毒理學,如果對人類健康有更廣泛的益處,鼓勵報告生態(tài)系統(tǒng)內生物的毒理學數(shù)據(jù)。臨床毒理學,有關毒理學研究的臨床試驗或藥物應用的研究,包括轉化毒理學,研究將臨床應用的毒性反應的分子理解轉化為臨床應用。食品毒理學,與食品和營養(yǎng)有關的化學提取物的毒理學研究。涉及無特征提取物或其中食物僅具有有限或當?shù)乩娴难芯繎谄渌胤教峤弧7治鲇嬃繉W,包括新分析方法和應用的研究
Toxicology Research aims to publish cutting edge research that is excellent and innovative, that drives toxicology and has international impact. Articles should cover chemical or biological aspects of the toxic response and the mechanisms involved.The journal''s scope includes the following.Nanotoxicology, studies on the biochemical or molecular mechanisms of toxic responses to nanomaterials and common nanomaterials which are of direct relevance to human health, are strongly encouraged. Carcinogenicity, including studies on mode of action of carcinogens, genotoxicity and mutationBiomarkers of toxicity, including studies on their identification, validation, and utilisationComputational and predictive toxicology, including in vitro, in vivo and in silico studies of toxicity and the development of predictive tools and models. Work considering alternative methods to in vivo studies is encouraged.Systems toxicology, studies that describe the toxicological effects of chemicals on specific organs or systems (for example, immune, nervous, reproductive, respiratory), including studies that incorporate genomic, metabonomic and proteomic dataRisk assessment, studies which provide toxicological data or information – such as hazard identification, dose-response assessmentExposure assessment for the development of risk assessments or regulationEnvironmental toxicology, studies reporting toxicology data for organisms within an ecosystem are encouraged if there is a wider benefit to human health.Clinical toxicology, studies relating to clinical trials or medicinal applications of toxicological research, including translational toxicology, Studies translating a molecular understanding of the toxic response to clinical application.Food toxicology, toxicological studies of chemical extracts related to food and nutrition. Studies that involve uncharacterised extracts or in which the food substance is only of limited or local interest should be submitted elsewhere.Analytical metrology, including studies of new analytical methods and applications
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